Member 11 Subfamily B ATP Binding Cassette Transporter

ATP-binding cassette, subfamily B, protein (P-glycoproteins) that functions in the ATP-dependent secretion of BILE SALTS into the BILE CANALICULI of HEPATOCYTES. Mutations in the ABCB11 gene are associated with progressive familial intrahepatic cholestasis 2 (see CHOLESTASIS, INTRAHEPATIC).

Also Known As:

ATP Binding Cassette Transporter, Subfamily B, Member 11; ABCB11 Protein; ATP Binding Cassette Subfamily B Member 11; ATP Binding Cassette Transporter, Sub-Family B, Member 11; BSEP Protein; Bile Salt Export Pump

Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - ATP-Binding Cassette Transporters: 2845
        Subfamily B ATP Binding Cassette Transporter: 258
        Member 11 Subfamily B ATP Binding Cassette Transporter: 278
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - ATP-Binding Cassette Transporters: 2845
        Subfamily B ATP Binding Cassette Transporter: 258
        Member 11 Subfamily B ATP Binding Cassette Transporter: 278
  - Carrier Proteins: 12999
    - Membrane Transport Proteins: 589
      - ATP-Binding Cassette Transporters: 2845
        Subfamily B ATP Binding Cassette Transporter: 258
        Member 11 Subfamily B ATP Binding Cassette Transporter: 278
      - Ion Pumps: 61
        Anion Transport Proteins: 2
        Organic Anion Transporters: 371
        ATP-Dependent Organic Anion Transporters
        Subfamily B ATP Binding Cassette Transporter: 258
        Member 11 Subfamily B ATP Binding Cassette Transporter: 278
  - Membrane Proteins: 10078
    - Membrane Glycoproteins: 2252
      - ATP-Binding Cassette Transporters: 2845
        Subfamily B ATP Binding Cassette Transporter: 258
        Member 11 Subfamily B ATP Binding Cassette Transporter: 278
    - Membrane Transport Proteins: 589
      - ATP-Binding Cassette Transporters: 2845
        Subfamily B ATP Binding Cassette Transporter: 258
        Member 11 Subfamily B ATP Binding Cassette Transporter: 278
      - Ion Pumps: 61
        Anion Transport Proteins: 2
        Organic Anion Transporters: 371
        ATP-Dependent Organic Anion Transporters
        Subfamily B ATP Binding Cassette Transporter: 258
        Member 11 Subfamily B ATP Binding Cassette Transporter: 278

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Olaf Mol Research Topics

Disease

Drug/Important Bio-Agent (IBA)